For centuries, science tested theories against the real world. Today, in fields from medicine to climate science to AI, theories are increasingly tested against simulations, models that predict how reality should behave. Critics warn these predictions often embed assumptions and biases. Breakthroughs like AlphaFold and AI-driven drug design raise a provocative question: are we discovering reality or the worldview of our models?

The Simulation Matrix is a live event exploring this critical shift. Join IAI Live January to experience:

     A live debate with leading scientists and philosophers including John Ioannidis, Steve Koonin & Paulette Clancy.

     A live interview with Jürgen Schmidhuber on the promises and limits of simulation

     A live solo talk with Philip Mirowski on the future of scientific method

This event is free for Premium Live subscribers, with pay-per-view tickets also available. Join us to question what we know, confront the assumptions behind science, and explore the frontier where data, discovery, and doubt collide.